[Gln8]-C517 (LH-RH), chicken - Ontores  

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[Gln8]-C517 (LH-RH), chicken

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名称 [Gln8]-C517 (LH-RH), chicken
CAS No. 47922-48-5
目录号 ONP10629
规格 mg/g
纯度 ≥98%
价格 更多在线询价
贮存 -20°C
分子量 1154.23
序列结构 H-pGLU-HIS-TRP-SER-TYR-GLY-LEU-GLN-PRO-GLY-OH
库存
产品简述 [Gln8] Luteinizing hormone releasing hormone ([Gln8] LH-RH), Avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions. It has been assumed, usually with good reason, that D-amino acids with large aromatic side-chains must be present in position 6 of both LH-RH superagonists and antagonists for the highest levels of biological activity to be reached. However, using one of a recent generation of potent lH-RH inhibitory analogs as a model, we have found that the insertion of D-lysine or, better still, D-arginine in this position results in greater antiovulatory activity in the rat over corresponding D-phenylalanine6- and D-tryptophan6-analogs.